Catalog NumberYM88495630
CAS Number88495-63-0
CategoryADCs
Description
Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69. It is a potential inhibitor of STAT-3 and exhibits selective cytotoxicity of cancer cells over normal cells in vitro
Synonyms
Artesunic acid
IUPAC Name
4-Oxo-4-[[(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoicacid
Molecular Weight
384.42
Molecular Formula
C19H28O8
Canonical SMILES
C[C@@H]1CC[C@H]2[C@H]([C@@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC(=O)CCC(=O)O)C
InChI
InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16-,17-,18-,19-/m1/s1
InChI Key
FIHJKUPKCHIPAT-AHIGJZGOSA-N
Purity
98% Min.
Storage
Store at -20°C
EC Number
618-170-5
Endotoxin Levels
<1 EU/mg
Form
Powder
Impurity Content
2% Max.
MDL Number
MFCD00866204
Size
10 mg; 50 mg